DTR not working in serial communication

I attempted to use DTR mode in serial communication, but it did not work when connected to the device. I would like to know if there is a solution.

Window1.Serial1.SerialPort = System.SerialPort(Window1.Setup1.Port.ListIndex)
Window1.Serial1.DTR = True

Did you follow the advice on DTR?

Changing property values does not automatically change the state of the hardware, you must call Reset or re-Open the connection in order for the change to take effect.