Xojo 2025 R2.1 crashing randomly while launching app in the Simulator

FWIW, it was already discussed recently: 2025r2.1 Tahoe 26.0.1 (25A362) Xojo Crash
Not sure it’s the same issue as yours, but may worth a check.

It’s good practice to always do that, even without crash.
Especially since the IDE can’t recover unsaved projects as of now; this drives me crazy…