Damn! I just found a similar, if not the same, problem. I had a Desktop app open in the IDE and selected “Hide the Toolbar” from the View menu. Then I closed Xojo. Now, whenever I open Xojo, the toolbar space is there but has no buttons in it until I select “Show Toolbar” from the View menu.
I did some more testing and found that this problem does not always crop up, but when it does it is persistent. In my report I added a way to resolve it on the local level but you need to be comfortable editing your machine’s registry (Windows obviously).