Your linux system is missing some of the required libraries.
See: System requirements — Xojo documentation
You may need to install extra libraries if possible.
Should I try using Ubuntu LTS on a separate SSD rather than tweaking my current Mint version based on this?
That is up to you, I don’t have experience with running the IDE on Linux.
Hope this helps:
sudo apt search libglib
This gives you a long list of libglib**.deb names
sudo apt install --reinstall libglib2.0-0t64 libglib2.0-data libglibmm-2.4-1t64
Those are installed in my Linux Mint (same version as yours).