Web 2.0 disabled items

In Web 1.0, when I have a button (or other object) disabled, I not only set XXX.Enabled = False, but I give it a special greyish WebStyle.

Will I need to set the WebStyle colour in Web 2.0, or will BootStrap and it’s CSS handle this for me?

The appearance of disabled controls was an area that we were very specific about this time. Bootstrap does handle a large portion of the appearance, but we are also not disabling controls more than once in Web 2.0.